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Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARα

Fenofibrate, a specific agonist of peroxisome proliferator–activated receptor-α (PPARα), displays robust therapeutic effects on diabetic retinopathy (DR) in patients with type 2 diabetes. Our recent studies have shown that PPARα is downregulated in the diabetic retina, which contributes to the patho...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Qiu, Fangfang, Zhou, Kelu, Matlock, H. Greg, Takahashi, Yusuke, Rajala, Raju V.S., Yang, Yanhui, Moran, Elizabeth, Ma, Jian-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440012/
https://www.ncbi.nlm.nih.gov/pubmed/28270521
http://dx.doi.org/10.2337/db16-1246