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Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis

Glucocorticoids promote lipolysis in white adipose tissue (WAT) to adapt to energy demands under stress, whereas superfluous lipolysis causes metabolic disorders, including dyslipidemia and hepatic steatosis. Glucocorticoid-induced lipolysis requires the phosphorylation of cytosolic hormone-sensitiv...

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Detalles Bibliográficos
Autores principales: Kuo, Taiyi, Chen, Tzu-Chieh, Lee, Rebecca A., Nguyen, Nguyen Huynh Thao, Broughton, Augusta E., Zhang, Danyun, Wang, Jen-Chywan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440017/
https://www.ncbi.nlm.nih.gov/pubmed/28292967
http://dx.doi.org/10.2337/db16-0831