Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E(2) Signaling and Enhances Diabetic β-Cell Function

Prostaglandin E(2) (PGE(2)) is derived from arachidonic acid, whereas PGE(3) is derived from eicosapentaenoic acid (EPA) using the same downstream metabolic enzymes. Little is known about the impact of EPA and PGE(3) on β-cell function, particularly in the diabetic state. In this work, we determined...

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Detalles Bibliográficos
Autores principales: Neuman, Joshua C., Schaid, Michael D., Brill, Allison L., Fenske, Rachel J., Kibbe, Carly R., Fontaine, Danielle A., Sdao, Sophia M., Brar, Harpreet K., Connors, Kelsey M., Wienkes, Haley N., Eliceiri, Kevin W., Merrins, Matthew J., Davis, Dawn B., Kimple, Michelle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440023/
https://www.ncbi.nlm.nih.gov/pubmed/28193789
http://dx.doi.org/10.2337/db16-1362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440023/
https://www.ncbi.nlm.nih.gov/pubmed/28193789
http://dx.doi.org/10.2337/db16-1362

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