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Zinc blocks SOS-induced antibiotic resistance via inhibition of RecA in Escherichia coli

Zinc inhibits the virulence of diarrheagenic E. coli by inducing the envelope stress response and inhibiting the SOS response. The SOS response is triggered by damage to bacterial DNA. In Shiga-toxigenic E. coli, the SOS response strongly induces the production of Shiga toxins (Stx) and of the bacte...

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Detalles Bibliográficos
Autores principales: Bunnell, Bryan E., Escobar, Jillian F., Bair, Kirsten L., Sutton, Mark D., Crane, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440055/
https://www.ncbi.nlm.nih.gov/pubmed/28542496
http://dx.doi.org/10.1371/journal.pone.0178303