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Development of a novel chronic kidney disease mouse model to evaluate the progression of hyperphosphatemia and associated mineral bone disease

Medial arterial calcification (MAC) and renal osteodystrophy are complications of mineral bone disease (MBD) associated with chronic kidney disease (CKD). Our aim was to develop a novel mouse model to investigate the clinical course of CKD-MBD. Eight-week-old C57BL/6 J male mice were assigned to the...

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Detalles Bibliográficos
Autores principales: Tani, Takashi, Orimo, Hideo, Shimizu, Akira, Tsuruoka, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440375/
https://www.ncbi.nlm.nih.gov/pubmed/28533541
http://dx.doi.org/10.1038/s41598-017-02351-6