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Prostaglandin E(2) inhibits matrix mineralization by human bone marrow stromal cell-derived osteoblasts via Epac-dependent cAMP signaling
The osteoinductive properties of prostaglandin E(2) (PGE(2)) and its signaling pathways have led to suggestions that it may serve as a potential therapeutic strategy for bone loss. However, the prominence of PGE(2) as an inducer of bone formation is attributed primarily to findings from studies usin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440379/ https://www.ncbi.nlm.nih.gov/pubmed/28533546 http://dx.doi.org/10.1038/s41598-017-02650-y |