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Kinetic interpretation of log-logistic dose-time response curves

A Hill-type time-response curve was derived using a single-step chemical kinetics approximation. The rate expression for the transformation is a differential equation that provides an interpolation formula between the logistic growth curve and second order kinetics. The solution is equivalent to the...

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Detalles Bibliográficos
Autores principales: Focke, Walter W., van der Westhuizen, Isbe, Musee, Ndeke, Loots, Mattheüs Theodor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440384/
https://www.ncbi.nlm.nih.gov/pubmed/28533508
http://dx.doi.org/10.1038/s41598-017-02474-w