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Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

Observational studies on smoking and risk of hay fever and asthma have shown inconsistent results. However, observational studies may be biased by confounding and reverse causation. Mendelian randomization uses genetic variants as markers of exposures to examine causal effects. We examined the causa...

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Detalles Bibliográficos
Autores principales: Skaaby, Tea, Taylor, Amy E., Jacobsen, Rikke K., Paternoster, Lavinia, Thuesen, Betina H., Ahluwalia, Tarunveer S., Larsen, Sofus C., Zhou, Ang, Wong, Andrew, Gabrielsen, Maiken E., Bjørngaard, Johan H., Flexeder, Claudia, Männistö, Satu, Hardy, Rebecca, Kuh, Diana, Barry, Sarah J., Tang Møllehave, Line, Cerqueira, Charlotte, Friedrich, Nele, Bonten, Tobias N., Noordam, Raymond, Mook-Kanamori, Dennis O., Taube, Christian, Jessen, Leon E., McConnachie, Alex, Sattar, Naveed, Upton, Mark N., McSharry, Charles, Bønnelykke, Klaus, Bisgaard, Hans, Schulz, Holger, Strauch, Konstantin, Meitinger, Thomas, Peters, Annette, Grallert, Harald, Nohr, Ellen A., Kivimaki, Mika, Kumari, Meena, Völker, Uwe, Nauck, Matthias, Völzke, Henry, Power, Chris, Hyppönen, Elina, Hansen, Torben, Jørgensen, Torben, Pedersen, Oluf, Salomaa, Veikko, Grarup, Niels, Langhammer, Arnulf, Romundstad, Pål R., Skorpen, Frank, Kaprio, Jaakko, R Munafò, Marcus, Linneberg, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440386/
https://www.ncbi.nlm.nih.gov/pubmed/28533558
http://dx.doi.org/10.1038/s41598-017-01977-w