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Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries

CRISPR-Cas9 technology has accelerated biological research becoming routine for many laboratories. It is rapidly replacing conventional gene editing techniques and has high utility for both genome-wide and gene-focussed applications. Here we present the first individually cloned CRISPR-Cas9 genome w...

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Detalles Bibliográficos
Autores principales: Metzakopian, Emmanouil, Strong, Alex, Iyer, Vivek, Hodgkins, Alex, Tzelepis, Konstantinos, Antunes, Liliana, Friedrich, Mathias J, Kang, Qiaohua, Davidson, Teresa, Lamberth, Jacob, Hoffmann, Christina, Davis, Gregory D., Vassiliou, George S., Skarnes, William C., Bradley, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440395/
https://www.ncbi.nlm.nih.gov/pubmed/28533524
http://dx.doi.org/10.1038/s41598-017-01766-5