Cargando…

Perivascular AQP4 dysregulation in the hippocampal CA1 area after traumatic brain injury is alleviated by adenosine A(2A) receptor inactivation

Traumatic brain injury (TBI) can induce cognitive dysfunction due to the regional accumulation of hyperphosphorylated tau protein (p-tau). However, the factors that cause p-tau to concentrate in specific brain regions remain unclear. Here, we show that AQP4 polarization in the perivascular astrocyti...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Zi-Ai, Li, Ping, Ye, Shi-Yang, Ning, Ya-Lei, Wang, Hao, Peng, Yan, Yang, Nan, Zhao, Yan, Zhang, Zhuo-Hang, Chen, Jiang-Fan, Zhou, Yuan-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440401/
https://www.ncbi.nlm.nih.gov/pubmed/28533515
http://dx.doi.org/10.1038/s41598-017-02505-6