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Kif4A mediate the accumulation and reeducation of THP-1 derived macrophages via regulation of CCL2-CCR2 expression in crosstalking with OSCC

Crosstalk between tumor infiltrating macrophages and tumor cells is thought to play an indispensable role in oral squamous cell carcinomas (OSCC) by induction and maintenance of tolerance microenvironment. High infiltration of M2 macrophages and increasing expression of Kinesin family member 4A (Kif...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Liu, Shaohua, Qu, Daiwei, Wang, Ketao, Zhang, Lin, Jing, Xuanxuan, Li, Chen, Wei, Fengcai, Qu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440405/
https://www.ncbi.nlm.nih.gov/pubmed/28533507
http://dx.doi.org/10.1038/s41598-017-02261-7