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Regulation of GVBD in mouse oocytes by miR-125a-3p and Fyn kinase through modulation of actin filaments

Meiotically arrested oocytes are characterized by the presence of the nuclear structure known as germinal-vesicle (GV), the breakdown of which (GVBD) is associated with resumption of meiosis. Fyn is a pivotal factor in resumption of the first meiotic division; its inhibition markedly decreases the f...

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Detalles Bibliográficos
Autores principales: Grossman, Hadas, Har-Paz, Efrat, Gindi, Natalie, Levi, Mattan, Miller, Irit, Nevo, Nava, Galiani, Dalia, Dekel, Nava, Shalgi, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440411/
https://www.ncbi.nlm.nih.gov/pubmed/28533542
http://dx.doi.org/10.1038/s41598-017-02071-x