The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence

PR domain containing protein 9 (PRDM9) is a meiosis-specific, multi-domain protein that regulates the location of recombination hotspots by targeting its DNA recognition sequence for double-strand breaks (DSBs). PRDM9 specifically recognizes DNA via its tandem array of zinc fingers (ZnFs), epigeneti...

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Detalles Bibliográficos
Autores principales: Striedner, Yasmin, Schwarz, Theresa, Welte, Thomas, Futschik, Andreas, Rant, Ulrich, Tiemann-Boege, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440498/
https://www.ncbi.nlm.nih.gov/pubmed/28155083
http://dx.doi.org/10.1007/s10577-017-9552-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440498/
https://www.ncbi.nlm.nih.gov/pubmed/28155083
http://dx.doi.org/10.1007/s10577-017-9552-1

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