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The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence
PR domain containing protein 9 (PRDM9) is a meiosis-specific, multi-domain protein that regulates the location of recombination hotspots by targeting its DNA recognition sequence for double-strand breaks (DSBs). PRDM9 specifically recognizes DNA via its tandem array of zinc fingers (ZnFs), epigeneti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440498/ https://www.ncbi.nlm.nih.gov/pubmed/28155083 http://dx.doi.org/10.1007/s10577-017-9552-1 |