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Long-Term Assessment of AAV-Mediated Zinc Finger Nuclease Expression in the Mouse Brain

Gene editing tools like TALENs, ZFNs and Crispr/Cas now offer unprecedented opportunities for targeted genetic manipulations in virtually all species. Most of the recent research in this area has concentrated on manipulation of the genome in isolated cells, which then give rise to transgenic animals...

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Detalles Bibliográficos
Autores principales: Zahur, Muzna, Tolö, Johan, Bähr, Mathias, Kügler, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440507/
https://www.ncbi.nlm.nih.gov/pubmed/28588449
http://dx.doi.org/10.3389/fnmol.2017.00142