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Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial

The RTS,S candidate malaria vaccine can protect against controlled human malaria infection (CHMI), but how protection is achieved remains unclear. Here, we have analyzed longitudinal peripheral blood transcriptome and immunogenicity data from a clinical efficacy trial in which healthy adults receive...

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Detalles Bibliográficos
Autores principales: van den Berg, Robert A., Coccia, Margherita, Ballou, W. Ripley, Kester, Kent E., Ockenhouse, Christian F., Vekemans, Johan, Jongert, Erik, Didierlaurent, Arnaud M., van der Most, Robbert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440508/
https://www.ncbi.nlm.nih.gov/pubmed/28588574
http://dx.doi.org/10.3389/fimmu.2017.00557