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Neurovascular Unit Dysfunction and Blood–Brain Barrier Hyperpermeability Contribute to Schizophrenia Neurobiology: A Theoretical Integration of Clinical and Experimental Evidence

Schizophrenia is a psychotic disorder characterized by delusions, hallucinations, negative symptoms, as well as behavioral and cognitive dysfunction. It is a pathoetiologically heterogeneous disorder involving complex interrelated mechanisms that include oxidative stress and neuroinflammation. Neuro...

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Detalles Bibliográficos
Autores principales: Najjar, Souhel, Pahlajani, Silky, De Sanctis, Virginia, Stern, Joel N. H., Najjar, Amanda, Chong, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440518/
https://www.ncbi.nlm.nih.gov/pubmed/28588507
http://dx.doi.org/10.3389/fpsyt.2017.00083