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Splenic Ly6C(hi) monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient mice

Heme oxygenase-1 (Hmox1) is a stress-inducible protein crucial in heme catabolism. The end products of its enzymatic activity possess anti-oxidative, anti-apoptotic and anti-inflammatory properties. Cardioprotective effects of Hmox1 were demonstrated in experimental models of myocardial infarction (...

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Detalles Bibliográficos
Autores principales: Tomczyk, Mateusz, Kraszewska, Izabela, Szade, Krzysztof, Bukowska-Strakova, Karolina, Meloni, Marco, Jozkowicz, Alicja, Dulak, Jozef, Jazwa, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440541/
https://www.ncbi.nlm.nih.gov/pubmed/28534119
http://dx.doi.org/10.1007/s00395-017-0629-y