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Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron

Hemin plays a key role in mediating secondary neuronal injury after intracerebral hemorrhage (ICH) and the cell toxicity of hemin is thought to be due to iron that is liberated when hemin is degraded. In a recent study, we demonstrated the iron regulatory hormone hepcidin reduces brain iron in iron-...

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Detalles Bibliográficos
Autores principales: Zhou, Yu-Fu, Zhang, Chao, Yang, Guang, Qian, Zhong-Ming, Zhang, Meng-Wan, Ma, Juan, Zhang, Fa-Li, Ke, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440571/
https://www.ncbi.nlm.nih.gov/pubmed/28588503
http://dx.doi.org/10.3389/fphys.2017.00332