Cargando…
T Cell Costimulation by CD6 Is Dependent on Bivalent Binding of a GADS/SLP-76 Complex
The cell surface receptor CD6 regulates T cell activation in both activating and inhibitory manners. The adaptor protein SLP-76 is recruited to the phosphorylated CD6 cytoplasmic Y662 residue during T cell activation, providing an activating signal to T cells. In this study, a biochemical approach i...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440646/ https://www.ncbi.nlm.nih.gov/pubmed/28289074 http://dx.doi.org/10.1128/MCB.00071-17 |