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Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment

Adoptive cell transfer utilizing tumour-targeting cytotoxic T lymphocytes (CTLs) is one of the most effective immunotherapies against haematological malignancies, but significant clinical success has not yet been achieved in solid tumours due in part to the strong immunosuppressive tumour microenvir...

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Detalles Bibliográficos
Autores principales: Kim, Kyun-Do, Bae, Seyeon, Capece, Tara, Nedelkovska, Hristina, de Rubio, Rafael G., Smrcka, Alan V., Jun, Chang-Duk, Jung, Woojin, Park, Byeonghak, Kim, Tae-il, Kim, Minsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440668/
https://www.ncbi.nlm.nih.gov/pubmed/28504276
http://dx.doi.org/10.1038/ncomms15365