Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins

Sirt1 is an NAD(+)-dependent protein deacetylase that regulates many physiological functions, including stress resistance, adipogenesis, cell senescence and energy production. Sirt1 can be activated by energy deprivation, but the mechanism is poorly understood. Here, we report that Sirt1 is negative...

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Detalles Bibliográficos
Autores principales: Kang, Hyeog, Oka, Shinichi, Lee, Duck-Yeon, Park, Junhong, Aponte, Angel M., Jung, Young-Sang, Bitterman, Jacob, Zhai, Peiyong, He, Yi, Kooshapur, Hamed, Ghirlando, Rodolfo, Tjandra, Nico, Lee, Sean B., Kim, Myung K., Sadoshima, Junichi, Chung, Jay H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440690/
https://www.ncbi.nlm.nih.gov/pubmed/28504272
http://dx.doi.org/10.1038/ncomms15560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440690/
https://www.ncbi.nlm.nih.gov/pubmed/28504272
http://dx.doi.org/10.1038/ncomms15560

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