Acute Knockdown of Kv4.1 Regulates Repetitive Firing Rates and Clock Gene Expression in the Suprachiasmatic Nucleus and Daily Rhythms in Locomotor Behavior

Rapidly activating and inactivating A-type K(+) currents (I(A)) encoded by Kv4.2 and Kv4.3 pore-forming (α) subunits of the Kv4 subfamily are key regulators of neuronal excitability. Previous studies have suggested a role for Kv4.1 α-subunits in regulating the firing properties of mouse suprachiasma...

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Detalles Bibliográficos
Autores principales: Hermanstyne, Tracey O., Granados-Fuentes, Daniel, Mellor, Rebecca L., Herzog, Erik D., Nerbonne, Jeanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440767/
https://www.ncbi.nlm.nih.gov/pubmed/28560311
http://dx.doi.org/10.1523/ENEURO.0377-16.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440767/
https://www.ncbi.nlm.nih.gov/pubmed/28560311
http://dx.doi.org/10.1523/ENEURO.0377-16.2017

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