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Acute Knockdown of Kv4.1 Regulates Repetitive Firing Rates and Clock Gene Expression in the Suprachiasmatic Nucleus and Daily Rhythms in Locomotor Behavior
Rapidly activating and inactivating A-type K(+) currents (I(A)) encoded by Kv4.2 and Kv4.3 pore-forming (α) subunits of the Kv4 subfamily are key regulators of neuronal excitability. Previous studies have suggested a role for Kv4.1 α-subunits in regulating the firing properties of mouse suprachiasma...
Autores principales: | Hermanstyne, Tracey O., Granados-Fuentes, Daniel, Mellor, Rebecca L., Herzog, Erik D., Nerbonne, Jeanne M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440767/ https://www.ncbi.nlm.nih.gov/pubmed/28560311 http://dx.doi.org/10.1523/ENEURO.0377-16.2017 |
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