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An evolutionary switch in ND2 enables Src kinase regulation of NMDA receptors
The non-receptor tyrosine kinase Src is a key signalling hub for upregulating the function of N-methyl D-aspartate receptors (NMDARs). Src is anchored within the NMDAR complex via NADH dehydrogenase subunit 2 (ND2), a mitochondrially encoded adaptor protein. The interacting regions between Src and N...
Autores principales: | Scanlon, David P., Bah, Alaji, Krzeminski, Mickaël, Zhang, Wenbo, Leduc-Pessah, Heather L., Dong, Yi Na, Forman-Kay, Julie D., Salter, Michael W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440837/ https://www.ncbi.nlm.nih.gov/pubmed/28508887 http://dx.doi.org/10.1038/ncomms15220 |
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