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Gonadotoxic Effects of Nilotinib in Chronic Myeloid Leukemia Treatment Dose in a Mouse Model

OBJECTIVE: Tyrosine kinase inhibitors may have deleterious effects on spermatogenesis or folliculogenesis, resulting in male or female subfertility. The aim of this study is to determine the effect of nilotinib, which is used routinely to treat chronic myeloid leukemia, on spermatogenesis and follic...

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Detalles Bibliográficos
Autores principales: Cengiz Seval, Güldane, Özkavukçu, Sinan, Seval, Murat, Aylı, Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440865/
https://www.ncbi.nlm.nih.gov/pubmed/27466938
http://dx.doi.org/10.4274/tjh.2016.0092