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Gonadotoxic Effects of Nilotinib in Chronic Myeloid Leukemia Treatment Dose in a Mouse Model
OBJECTIVE: Tyrosine kinase inhibitors may have deleterious effects on spermatogenesis or folliculogenesis, resulting in male or female subfertility. The aim of this study is to determine the effect of nilotinib, which is used routinely to treat chronic myeloid leukemia, on spermatogenesis and follic...
Autores principales: | Cengiz Seval, Güldane, Özkavukçu, Sinan, Seval, Murat, Aylı, Meltem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440865/ https://www.ncbi.nlm.nih.gov/pubmed/27466938 http://dx.doi.org/10.4274/tjh.2016.0092 |
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