Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease (PASTIS): study protocol for a randomised controlled trial

BACKGROUND: Cerebral small vessel disease is a common cause of vascular cognitive impairment in older people, with no licensed treatment. Cerebral blood flow is reduced in small vessel disease. Tadalafil is a widely prescribed phosphodiesterase-5 inhibitor that increases blood flow in other vascular...

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Detalles Bibliográficos
Autores principales: Pauls, Mathilde M. H., Clarke, Natasha, Trippier, Sarah, Betteridge, Shai, Howe, Franklyn A., Khan, Usman, Kruuse, Christina, Madigan, Jeremy B., Moynihan, Barry, Pereira, Anthony C., Rolfe, Debbie, Rostrup, Egill, Haig, Caroline E., Barrick, Thomas R., Isaacs, Jeremy D., Hainsworth, Atticus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440904/
https://www.ncbi.nlm.nih.gov/pubmed/28532471
http://dx.doi.org/10.1186/s13063-017-1973-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440904/
https://www.ncbi.nlm.nih.gov/pubmed/28532471
http://dx.doi.org/10.1186/s13063-017-1973-9

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