The F-actin modulator SWAP-70 controls podosome patterning in osteoclasts

Osteoclasts are bone resorbing cells acting as key mediators of bone disorders. Upon adhesion to bone, osteoclasts polarize and reorganize their cytoskeleton to generate a ring-like F-actin-rich structure, the sealing zone, wherein the osteoclast's resorptive organelle, the ruffled border, is f...

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Detalles Bibliográficos
Autores principales: Roscher, Anne, Hasegawa, Tomoka, Dohnke, Sebastian, Ocaña-Morgner, Carlos, Amizuka, Norio, Jessberger, Rolf, Garbe, Annette I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440945/
https://www.ncbi.nlm.nih.gov/pubmed/28580389
http://dx.doi.org/10.1016/j.bonr.2016.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440945/
https://www.ncbi.nlm.nih.gov/pubmed/28580389
http://dx.doi.org/10.1016/j.bonr.2016.07.002

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