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Extremely low-coverage whole genome sequencing in South Asians captures population genomics information

BACKGROUND: The cost of Whole Genome Sequencing (WGS) has decreased tremendously in recent years due to advances in next-generation sequencing technologies. Nevertheless, the cost of carrying out large-scale cohort studies using WGS is still daunting. Past simulation studies with coverage at ~2x hav...

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Detalles Bibliográficos
Autores principales: Rustagi, Navin, Zhou, Anbo, Watkins, W. Scott, Gedvilaite, Erika, Wang, Shuoguo, Ramesh, Naveen, Muzny, Donna, Gibbs, Richard A., Jorde, Lynn B., Yu, Fuli, Xing, Jinchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440948/
https://www.ncbi.nlm.nih.gov/pubmed/28532386
http://dx.doi.org/10.1186/s12864-017-3767-6