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Glucocorticoid receptor-mediated cis-repression of osteogenic genes requires BRM-SWI/SNF()

Glucocorticoids are an effective therapy for a variety of severe inflammatory and autoimmune disorders; however, the therapeutic use of glucocorticoids is severely limited by their negative side effects, particularly on osteogenesis. Glucocorticoids regulate transcription by binding to the glucocort...

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Detalles Bibliográficos
Autores principales: Pico, Michael J., Hashemi, Sharareh, Xu, Fuhua, Nguyen, Kevin Hong, Donnelly, Robert, Moran, Elizabeth, Flowers, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440962/
https://www.ncbi.nlm.nih.gov/pubmed/28580390
http://dx.doi.org/10.1016/j.bonr.2016.07.006