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Positively Selected Sites at HCMV gB Furin Processing Region and Their Effects in Cleavage Efficiency

Human cytomegalovirus is a ubiquitous infectious agent that affects mainly immunosuppressed, fetuses, and newborns. The virus has several polymorphic regions, in particular in the envelope glycoproteins. The UL55 gene encodes the glycoprotein B that has a variable region, containing a furin cleavage...

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Detalles Bibliográficos
Autores principales: Stangherlin, Lucas M., de Paula, Felipe N., Icimoto, Marcelo Y., Ruiz, Leonardo G. P., Nogueira, Maurício L., Braz, Antônio S. K., Juliano, Luiz, da Silva, Maria C. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441137/
https://www.ncbi.nlm.nih.gov/pubmed/28588572
http://dx.doi.org/10.3389/fmicb.2017.00934