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Positively Selected Sites at HCMV gB Furin Processing Region and Their Effects in Cleavage Efficiency
Human cytomegalovirus is a ubiquitous infectious agent that affects mainly immunosuppressed, fetuses, and newborns. The virus has several polymorphic regions, in particular in the envelope glycoproteins. The UL55 gene encodes the glycoprotein B that has a variable region, containing a furin cleavage...
Autores principales: | Stangherlin, Lucas M., de Paula, Felipe N., Icimoto, Marcelo Y., Ruiz, Leonardo G. P., Nogueira, Maurício L., Braz, Antônio S. K., Juliano, Luiz, da Silva, Maria C. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441137/ https://www.ncbi.nlm.nih.gov/pubmed/28588572 http://dx.doi.org/10.3389/fmicb.2017.00934 |
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