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Synthesis and biological evaluation of novel imidazolidine derivatives as candidates to schistosomicidal agents

INTRODUCTION: Schistosomiasis is an infectious parasitic disease caused by trematodes of the genus Schistosoma, which threatens at least 258 million people worldwide and its control is dependent on a single drug, praziquantel. The aim of this study was to evaluate the anti-Schistosoma mansoni activi...

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Detalles Bibliográficos
Autores principales: Matos-Rocha, Thiago José, de Lima, Maria do Carmo Alves, da Silva, Anekécia Lauro, de Oliveira, Jamerson Ferreira, Gouveia, Allana Lemos Andrade, da Silva, Vinícius Barros Ribeiro, de Almeida, Antônio Sérgio Alves, Brayner, Fábio André, Cardoso, Pablo Ramon Gualberto, Pitta-Galdino, Marina da Rocha, Pitta, Ivan da Rocha, Rêgo, Moacyr Jesus Barreto de Melo, Alves, Luiz Carlos, Pitta, Maira Galdino da Rocha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441159/
https://www.ncbi.nlm.nih.gov/pubmed/28380119
http://dx.doi.org/10.1590/S1678-9946201759008