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Ezh2 Acts as a Tumor Suppressor in Kras-driven Lung Adenocarcinoma

Previous studies have suggested that enhancer zeste homolog 2 (Ezh2), a histone methyltransferase subunit of polycomb repressive complex 2 (PRC2), acts as an oncogene in lung adenocarcinoma (ADC) development. However, we found that in human lung ADC samples, deletion and mutations of EZH2 were also...

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Detalles Bibliográficos
Autores principales: Wang, Yanxiao, Hou, Ning, Cheng, Xuan, Zhang, Jishuai, Tan, Xiaohong, Zhang, Chong, Tang, Yuling, Teng, Yan, Yang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441181/
https://www.ncbi.nlm.nih.gov/pubmed/28539837
http://dx.doi.org/10.7150/ijbs.19108