Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects

Tropomyosin 1 (TPM1) is an essential sarcomeric component, stabilising the thin filament and facilitating actin's interaction with myosin. A number of sarcomeric proteins, such as alpha myosin heavy chain, play crucial roles in cardiac development. Mutations in these genes have been linked to c...

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Detalles Bibliográficos
Autores principales: England, Jennifer, Granados-Riveron, Javier, Polo-Parada, Luis, Kuriakose, Diji, Moore, Christopher, Brook, J. David, Rutland, Catrin S., Setchfield, Kerry, Gell, Christopher, Ghosh, Tushar K., Bu'Lock, Frances, Thornborough, Christopher, Ehler, Elisabeth, Loughna, Siobhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441184/
https://www.ncbi.nlm.nih.gov/pubmed/28359939
http://dx.doi.org/10.1016/j.yjmcc.2017.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441184/
https://www.ncbi.nlm.nih.gov/pubmed/28359939
http://dx.doi.org/10.1016/j.yjmcc.2017.03.006

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