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Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects
Tropomyosin 1 (TPM1) is an essential sarcomeric component, stabilising the thin filament and facilitating actin's interaction with myosin. A number of sarcomeric proteins, such as alpha myosin heavy chain, play crucial roles in cardiac development. Mutations in these genes have been linked to c...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441184/ https://www.ncbi.nlm.nih.gov/pubmed/28359939 http://dx.doi.org/10.1016/j.yjmcc.2017.03.006 |