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in vivo localization of the neuronal ceroid lipofuscinosis proteins, CLN3 and CLN7, at endogenous expression levels

The neuronal ceroid lipofuscinoses are a group of recessively inherited, childhood-onset neurodegenerative conditions. Several forms are caused by mutations in genes encoding putative lysosomal membrane proteins. Studies of the cell biology underpinning these disorders are hampered by the poor antig...

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Detalles Bibliográficos
Autores principales: Mohammed, Alamin, O'Hare, Megan B., Warley, Alice, Tear, Guy, Tuxworth, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441185/
https://www.ncbi.nlm.nih.gov/pubmed/28365214
http://dx.doi.org/10.1016/j.nbd.2017.03.015