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Transient Hypothyroidism: Dual Effect on Adult-Type Leydig Cell and Sertoli Cell Development

Transient neonatal 6-propyl-2-thiouracil (PTU) induced hypothyroidism affects Leydig and Sertoli cell numbers in the developing testis, resulting in increased adult testis size. The hypothyroid condition was thought to be responsible, an assumption questioned by studies showing that uninterrupted fe...

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Detalles Bibliográficos
Autores principales: Rijntjes, Eddy, Gomes, Marcos L. M., Zupanič, Nina, Swarts, Hans J. M., Keijer, Jaap, Teerds, Katja J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441398/
https://www.ncbi.nlm.nih.gov/pubmed/28588502
http://dx.doi.org/10.3389/fphys.2017.00323