Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults

Necator americanus Glutathione-S-Transferase-1 (Na-GST-1) plays a role in the digestion of host hemoglobin by adult N. americanus hookworms. Vaccination of laboratory animals with recombinant Na-GST-1 is associated with significant protection from challenge infection. Recombinant Na-GST-1 was expres...

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Detalles Bibliográficos
Autores principales: Diemert, David J., Freire, Janaína, Valente, Vanderson, Fraga, Carlos Geraldo, Talles, Frederico, Grahek, Shannon, Campbell, Doreen, Jariwala, Amar, Periago, Maria Victoria, Enk, Martin, Gazzinelli, Maria Flávia, Bottazzi, Maria Elena, Hamilton, Robert, Brelsford, Jill, Yakovleva, Anna, Li, Guangzhao, Peng, Jin, Correa-Oliveira, Rodrigo, Hotez, Peter, Bethony, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441635/
https://www.ncbi.nlm.nih.gov/pubmed/28464026
http://dx.doi.org/10.1371/journal.pntd.0005574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441635/
https://www.ncbi.nlm.nih.gov/pubmed/28464026
http://dx.doi.org/10.1371/journal.pntd.0005574

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