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D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain

ATP-binding cassette (ABC) transporters form a large family of transmembrane importers and exporters. Using two nucleotide-binding domains (NBDs), which form a canonical ATP-sandwich dimer at some point within the transport cycle, the transporters harness the energy from ATP binding and hydrolysis t...

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Detalles Bibliográficos
Autores principales: Vakkasoglu, Ahmet S., Srikant, Sriram, Gaudet, Rachelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441636/
https://www.ncbi.nlm.nih.gov/pubmed/28542489
http://dx.doi.org/10.1371/journal.pone.0178238