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Teng-Long-Bu-Zhong-Tang induces p21-dependent cell senescence in colorectal carcinoma LS174T cells via histone acetylation

Teng-Long-Bu-Zhong-Tang (TLBZT) is a Chinese herbal formula for colorectal carcinoma treatment. TLBZT effectively induces cell senescence in colorectal carcinoma, accompanied by p21 upregulation. In this study, we further explored the role of p21 in TLBZT-induced cell senescence, as well as the mech...

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Detalles Bibliográficos
Autores principales: Hu, Bing, An, Hong-Mei, Wang, Shuang-Shuang, Zheng, Jia-Lu, Yan, Xia, Huang, Xiao-Wei, Tian, Jian-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441675/
https://www.ncbi.nlm.nih.gov/pubmed/28572741
http://dx.doi.org/10.2147/JEP.S129272