An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2

The non-receptor tyrosine kinase proline-rich tyrosine kinase 2 (Pyk2) is a critical mediator of signaling from cell surface growth factor and adhesion receptors to cell migration, proliferation, and survival. Emerging evidence indicates that signaling by Pyk2 regulates hematopoietic cell response,...

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Detalles Bibliográficos
Autores principales: Meirson, Tomer, Samson, Abraham O, Gil-Henn, Hava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441678/
https://www.ncbi.nlm.nih.gov/pubmed/28572720
http://dx.doi.org/10.2147/DDDT.S136150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441678/
https://www.ncbi.nlm.nih.gov/pubmed/28572720
http://dx.doi.org/10.2147/DDDT.S136150

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