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An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2

The non-receptor tyrosine kinase proline-rich tyrosine kinase 2 (Pyk2) is a critical mediator of signaling from cell surface growth factor and adhesion receptors to cell migration, proliferation, and survival. Emerging evidence indicates that signaling by Pyk2 regulates hematopoietic cell response,...

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Detalles Bibliográficos
Autores principales:	Meirson, Tomer, Samson, Abraham O, Gil-Henn, Hava
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441678/ https://www.ncbi.nlm.nih.gov/pubmed/28572720 http://dx.doi.org/10.2147/DDDT.S136150

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