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Carvacrol derivatives as mushroom tyrosinase inhibitors; synthesis, kinetics mechanism and molecular docking studies

The present work describesthe development of highly potent mushroom tyrosinase inhibitor better than the standard kojic acid. Carvacrol derivatives 4a-f and 6a-d having substituted benzoic acid and cinnamic acidresidues were synthesized with the aim to possess potent tyrosinase inhibitory activity.T...

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Detalles Bibliográficos
Autores principales: Ashraf, Zaman, Rafiq, Muhammad, Nadeem, Humaira, Hassan, Mubashir, Afzal, Samina, Waseem, Muhammad, Afzal, Khurram, Latip, Jalifah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441849/
https://www.ncbi.nlm.nih.gov/pubmed/28542395
http://dx.doi.org/10.1371/journal.pone.0178069