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Automated deep-phenotyping of the vertebrate brain

Here, we describe an automated platform suitable for large-scale deep-phenotyping of zebrafish mutant lines, which uses optical projection tomography to rapidly image brain-specific gene expression patterns in 3D at cellular resolution. Registration algorithms and correlation analysis are then used...

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Detalles Bibliográficos
Autores principales: Allalou, Amin, Wu, Yuelong, Ghannad-Rezaie, Mostafa, Eimon, Peter M, Yanik, Mehmet Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441873/
https://www.ncbi.nlm.nih.gov/pubmed/28406399
http://dx.doi.org/10.7554/eLife.23379