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Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations

AIM: To characterize AXL receptor tyrosine kinase (AXL) expression in relationship to tumor protein P53 (TP53 gene, p53 protein) and its role in tumor invasion and response to therapy. METHODS: We used 14 cell lines, including 3 isogenic pairs carrying mutant/knockout p53, to gain insight into the r...

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Detalles Bibliográficos
Autores principales: Abdel-Rahman, Wael M, Al-khayyal, Noura A, Nair, Vidhya A, Aravind, S R, Saber-Ayad, Maha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442080/
https://www.ncbi.nlm.nih.gov/pubmed/28596680
http://dx.doi.org/10.3748/wjg.v23.i19.3440