Surface PEGylation of Mesoporous Silica Nanorods (MSNR): Effect on loading, release, and delivery of mitoxantrone in hypoxic cancer cells

Mesoporous silica nanomaterials show great potential to deliver chemotherapeutics for cancer treatment. The key challenges in the development of injectable mesoporous silica formulations are colloidal instability, hemolysis and inefficient drug loading and release. In this study, we evaluated the ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Wani, Amit, Savithra, Galbokka H. Layan, Abyad, Ayat, Kanvinde, Shrey, Li, Jing, Brock, Stephanie, Oupický, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442097/
https://www.ncbi.nlm.nih.gov/pubmed/28536462
http://dx.doi.org/10.1038/s41598-017-02531-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442097/
https://www.ncbi.nlm.nih.gov/pubmed/28536462
http://dx.doi.org/10.1038/s41598-017-02531-4

Ejemplares similares