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Surface PEGylation of Mesoporous Silica Nanorods (MSNR): Effect on loading, release, and delivery of mitoxantrone in hypoxic cancer cells
Mesoporous silica nanomaterials show great potential to deliver chemotherapeutics for cancer treatment. The key challenges in the development of injectable mesoporous silica formulations are colloidal instability, hemolysis and inefficient drug loading and release. In this study, we evaluated the ef...
Autores principales: | Wani, Amit, Savithra, Galbokka H. Layan, Abyad, Ayat, Kanvinde, Shrey, Li, Jing, Brock, Stephanie, Oupický, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442097/ https://www.ncbi.nlm.nih.gov/pubmed/28536462 http://dx.doi.org/10.1038/s41598-017-02531-4 |
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