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IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis

Myeloid cells, key players in atherosclerosis, take up and present antigens, leading to systemic and local T cell activation. The recruitment and activation of immune cells to the aorta in atherosclerosis is regulated by adhesion molecules, chemokines and cytokines. IL-27R is an immunoregulatory sig...

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Detalles Bibliográficos
Autores principales: Peshkova, Iuliia O., Fatkhullina, Aliia R., Mikulski, Zbigniew, Ley, Klaus, Koltsova, Ekaterina K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442117/
https://www.ncbi.nlm.nih.gov/pubmed/28536468
http://dx.doi.org/10.1038/s41598-017-01828-8